The following examples illustrate the use of the numerical
optimization-integration algorithms described in the previous section.
Work is measured in terms of the number of density function
evaluations needed for the integration to compute
.
The basic starting interval
was computed using the Pegasus
method; the cost for this is minimal because only univariate and
bivariate
values are required.
The initial bracketing interval
for
is given in the first row in each table, and the work for
that row is the work to compute the initial
,
and
values (with only
required to start the Newton iteration).
Subsequent rows show results of the iterations necessary to determine
to the specified accuracy.
Our first example used data for starch thickness taken from Hsu and Nelson
(1998). The desired CI's were for two-sided comparisons versus a control, with
, and
For
, we computed
and
. The following numerical optimization-integration
results were obtained.
Pegasus Method Results for
 |
 |
, Work |
|
2.220, 2.264, 2.324 |
-.01, .0005, .01 |
.22, 39952 |
|
2.220, 2.262, 2.264 |
-.01, .00001, .0005 |
.22, 51152 |
Newton Method Results for
 |
 |
, Work |
|
2.116, 2.220, 2.324 |
, -.01, |
.26, 11200 |
|
2.220, 2.261, 2.324 |
-.01, -.0002, |
.24, 28752 |
For
, we computed
,
and:
Pegasus Method Results for
 |
 |
, Work |
|
2.518,2.561,2.606 |
-.005, .0002, .006 |
.12, 146432 |
|
2.518,2.559,2.561 |
-.005,.00004,.0002 |
.12, 187984 |
Newton Method Results for
 |
 |
, Work |
|
2.429,2.518,2.606 |
, -.005, |
.14, 41552 |
|
2.518,2.557,2.606 |
-.005,-.0002, |
.13, 104880 |
|
2.557,2.559,2.606 |
-.0002,.00001, |
.12, 168208 |
Our second example is an all-pairwise comparisons example based on a one-way
ANOVA design with sample sizes
(see Westfall et.al., 1999).
We need two sided CI's with
, given
For
, we computed
,
and:
Pegasus Method Results for
 |
 |
, Work |
|
2.324,2.339,2.383 |
-.003,.0003,.009 |
.21, 86144 |
|
2.324,2.337,2.339 |
-.003,-.0002,.0003 |
.21, 127696 |
Newton Method Results for
 |
 |
, Work |
|
2.265,2.324,2.383 |
, -.003, |
.25, 41552 |
|
2.324,2.338,2.383 |
-.003,-.00006, |
.21, 68592 |
For
, we computed
,
and:
Pegasus Method Results for
 |
 |
, Work |
|
2.648,2.654,2.684 |
-.0006,-.00001,.003 |
.11, 255680 |
Newton Method Results for
 |
 |
, Work |
|
2.612,2.648,2.684 |
, -.0006, |
.13, 63328 |
|
2.648,2.654,2.684 |
-.0006,.00003, |
.12, 159504 |
The results from these example tests demonstrate that the algorithms
described in this paper provide feasible methods for computing
values for confidence intervals. Given good starting intervals
determined from bivariate distribution values, the numerical optimzation
based on the use of the Newton method is more efficient than optimization
based on the Pegasus method. These conclusions are also supported by
a variety of other examples that we have considered.
REFERENCES
- Dawson, D. and Sankoff, A. (1967),
'An Inequality for Probabilities',
Proc. AMS 18, pp. 504-507.
- Dunnett, C.W. and Sobel, M. (1954),
'A Bivariate Generalization of Student's t-Distribution, with Tables for
Certain Special Cases'
Biometrika 41, pp. 153-169.
- Genz, A. and Bretz, F. (1999),
`Numerical Computation of the Multivariate t Probabilities with Application
to Power Calculation of Multiple Contrasts',
J. Stat. Comput. Simul.63, pp. 361-378.
- Genz, A. and Bretz, F. (2000),
'Methods for the Computation of Multivariate t Probabilities', submitted and
available from the website: www.sci.wsu.edu/math/faculty/genz/homepage.
- Genz, A. and Kwong, K.S. (1999),
`Numerical Evaluation of Singular Multivariate Normal Distributions',
to appear in Journal of Statistical Computation and Simulation.
- Hochberg, Y., and Tamhane, A.C. (1987),
Multiple Comparison Procedures, John Wiley and Sons, New York.
- Hsu, Jason C. (1996),
Multiple Comparisons, Chapman and Hall, London.
- Hsu, Jason C. (1992),
'Simultaneous Inference in the General Linear Model',
J. Comput. Graph. Stat. 1, pp. 151-168.
- Hsu, Jason C. and Nelson, Barry (1998),
'Multiple Comparisons in the General Linear Model',
J. Comput. Graph. Stat. 7, pp. 23-41.
- Ralston, A., and Rabinowitz, P. (1978),
A First Course in Numerical Analysis, McGraw-Hill, New York.
- Somerville, P.N. (1997,
`Multiple Testing and Simultaneous Confidence Intervals: Calculation of
Constants'
Comp. Stat. & Data Analysis 25, pp. 217-223.
- Somerville, P.N. (1998),
`Numerical Computation of Multivariate Normal and Multivariate-t
Probabilities Over Convex Regions',
J. Comput. Graph. Stat. 7, pp. 529-545.
- Stoline, M.R. (1981),
'The Status of Multiple Comparisons: Simultaneous Estimation of All Pairwise
Comparisons in One-Way ANOVA Design',
The American Statistician 35, pp. 134-141.
- Tong, Y.L. (1990),
The Multivariate Normal Distribution,
Springer-Verlag, New York, New York.
- Westfall, P.H., Tobias, R.D., Rom D., and Wolfinger, R.D. (1999),
Multiple Comparisons and Multiple Tests using the SAS System,
SAS Institute Inc, Cary, NC.
2003-02-17